Prepare for the MTTC Integrated Science (Secondary) Test. Utilize flashcards and multiple-choice questions, each accompanied by hints and explanations. Achieve success in your exam journey!

Multiple Choice

What is the function of helicase during DNA replication?

Opening idea: DNA replication requires opening the double helix so each strand can serve as a template. Helicase does this by breaking the hydrogen bonds between base pairs, using energy from ATP to unwind the DNA and form the replication fork. This unwinding exposes single-stranded templates for DNA polymerases to copy. Stopping or stabilizing the single strands is done by protective proteins, not helicase. The actual synthesis of a new strand is carried out by DNA polymerase, and sealing any backbone breaks is done by DNA ligase.

Opening idea: DNA replication requires opening the double helix so each strand can serve as a template. Helicase does this by breaking the hydrogen bonds between base pairs, using energy from ATP to unwind the DNA and form the replication fork. This unwinding exposes single-stranded templates for DNA polymerases to copy. Stopping or stabilizing the single strands is done by protective proteins, not helicase. The actual synthesis of a new strand is carried out by DNA polymerase, and sealing any backbone breaks is done by DNA ligase.